• Leafly

Try These β-Caryophyllene Cannabis Strains for Pain & Inflammation Relief


Beta-caryophyllene is a common and often abundant terpene found in cannabis. Its distinctive flavor contributes to the spiciness of black pepper and can be found in high amounts in cloves, hops, and rosemary. It falls under the FDA’s “generally recognized as safe” classification, so large doses can be safely consumed.

Over the last decade, β-caryophyllene has gained the attention of scientists when it was discovered to be one of the first non-cannabinoids to directly activate cannabinoid receptors. Beta-caryophyllene-rich cannabis strains may therefore have specific medicinal effects due to this terpene’s effect on our endocannabinoid system.

Below, we will overview some of β-caryophyllene’s potential benefits and then describe which strains tend to have high levels of this terpene and how to find them.

The Potential Benefits of β-Caryophyllene

CB2 receptors are found in immune tissues throughout the body and are increased in the brain in disease or following injury. Their activation reduces inflammation, which lessens pain and reduces the damaging consequences that chronic inflammation has on brain function and risk for developing brain diseases.

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